Effect of iron on expression of superoxide dismutase byAeromonas salmonicidaand associated resistance to superoxide anion

Superoxide dismutase Superoxide dismutase

Effect of Superoxide Dismutase

This study assesses the effect of the superoxide anion scavenger superoxide dismutase on myocardial capillary permeability-surface area (PS) products for small hydrophilic molecules after ischemia and reperfusion. Open-chest dogs underwent a 20-minute occlusion of the left anterior descending coronary artery followed by 1 hour of reperfusion. Myocardial plasma flow rate and capillary extraction...

Superoxide dismutase-based third-generation biosensor for superoxide anion.

A third-generation biosensor for superoxide anion (O2-) was developed by immobilizing superoxide dismutase (SOD) on a self-assembled monolayer of cysteine on gold electrode; i.e., a SOD/cysteine-modified gold electrode (SOD/Cys/Au) was fabricated. A rapid and direct electron transfer of SOD was realized at the gold electrode by using the cysteine molecule as an electron-transfer promoter. The p...

Inhibitory effect of superoxide-generating quinones on superoxide dismutase.

The one-electron reduction of quinones to semiquinones and the subsequent autooxldatlon of the semlqulnone back to the quinone can generate large quantities of superoxide (0~) (1,2). This reductlon-oxldation process, known as redox cycling, is anion radical catalyzed by a variety of cellular flavoproteins and is thought to be responsible for many of the therapeutic and toxic effects of quinonoi...

Enhanced Expression of Superoxide Dismutase

The oxygen free radical system has been reported to be activated by influenza virus infection in the lungs. However, the involvement of oxygen radicals in viral myocarditis is still unknown. Captopril, an angiotensin-converting enzyme (ACE) inhibitor and potent free radical scavenger with a sulfhydryl group, was effective for the treatment of viral myocarditis, while enalapril, an ACE inhibitor...